24 Basophil Activation Test may facilitate ABPA diagnosis in CF patients

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[Basophil activation test in the diagnosis of allergy to medicines].

In this paper we study the reliability of the basophil activation test (BAT) in the "in-vitro" diagnosis of allergy to betalactams and to metamizol, and the sensitivity and specificity of the technique are analyzed. To this end, we studied 58 patients allergic to betalactam antibiotics with a positive cutaneous test facing any derivative of penicillin and 30 healthy controls who tolerated betal...

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Is basophil activation test (BAT) really useful for allergy diagnosis?

Dear Editor, both the paper by Pereira Santos et al and the Editorial on the latest issue of this Journal, stressed on the essential, fairly irreplaceable role of basophil activation test (BAT) in allergy diagnosis (1,2). Certainly, BAT is a cell-based test and in this sense it should give fundamental insights about the role of these circulating leukocytes in hypersensitivity reactions, chronic...

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Basophil Activation Test with Food Additives in Chronic Urticaria Patients

The role of food additives in chronic urticaria (CU) is still under investigation. In this study, we aimed to explore the association between food additives and CU by using the basophil activation test (BAT). The BAT using 15 common food additives was performed for 15 patients with CU who had a history of recurrent urticarial aggravation following intake of various foods without a definite food...

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Basophil Markers for Identification and Activation in the Indirect Basophil Activation Test by Flow Cytometry for Diagnosis of Autoimmune Urticaria

BACKGROUND The indirect basophil activation test using flow cytometry is a promising tool for autoimmune urticaria diagnosis. We aimed to identify better donor basophils (from atopic vs. non-atopic donors and interleukin-3 primed vs. unprimed basophils) and improve basophil identification and activation markers (eotaxin CC chemokine receptor-3 [CCR3] vs. CD123 and CD63 vs. CD203c). METHODS Do...

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Basophil activation test in allergic rhinitis.

903 a different perception on rhinitis, be it caused by an IgEor a non -IgE -mediated challenge, because CD63 is easily activated by nonallergic stimulation.4 Furthermore, the ability to perform an accurate BAT depends also on the gating strategy used by the test to catch basophils in the flow cytometry electronic capture.5 The Flow2CASTTM (BÜHLMANN, Schönenbuch, Switzerland) used by Leśniak et...

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ژورنال

عنوان ژورنال: Journal of Cystic Fibrosis

سال: 2015

ISSN: 1569-1993

DOI: 10.1016/s1569-1993(15)30201-0